SeffiHair® Hamburg – Regenerative Autologous Fat Treatment for Hair Loss

Biological support for weakened hair follicles and the scalp using the body’s own adipose tissue

The Details of the Seffiller® Treatment in Hamburg

Treatment duration
approx. 60–90 minutes
Social downtime
usually 2–3 days
Anesthesia
local anesthesia
Sessions
usually 1 session, individually customizable
Follow-ups
after 3, 6, and 12 months
Principle
Autologous fat treatment
Result
Regenerative effect over several months
Combination
Part of our hair therapy concept, such as with PRP/PRF, Regenera Activa®, or light therapy

Attending Doctors

Dr. med. Anna Brandenburg
Specialist in Dermatology
Focus areas: Aesthetic Dermatology, Hair Medicine, Laser Therapy
Dr. med. univ. Pamela Mai
Specialist in Dermatology and Venereology
Focus areas: Aesthetic Dermatology and Laser Medicine, Hair Medicine

Autologous Procedure for Hair Loss – SeffiHair® Hamburg

Are you noticing thinning hair? With SeffiHair® (Superficial Enhanced Fluid Fat Injection), we offer you a biologically based approach to treatment. This innovative procedure uses your own adipose tissue to create a cell-rich, regenerative fraction that naturally supports the microenvironment of weakened hair follicles. SeffiHair® is particularly beneficial for early to moderate hereditary hair loss and diffuse thinning. Whether this treatment is suitable for you will be clarified during our specialized hair consultation through a comprehensive medical history and diagnostics of your case. You are welcome to book your personal consultation appointment online or by phone, and together we will determine which elements of our hair therapy concept best suit your needs. Please note that SeffiHair® is a self-pay service and is generally not covered by health insurance providers. You will receive a written cost estimate from us for your review.

The Treatment Process

Prior to the actual treatment, a dermatological assessment of the hair loss is always required: only when the cause, pattern, and stage are known can we determine whether a regenerative autologous fat treatment of the scalp is appropriate.

Diagnostics & Planning

We begin by evaluating your scalp, the pattern of hair loss, hair density, and the progression to date. Only then do we determine whether SeffiHair® matches your clinical findings or if an alternative hair therapy concept would be more suitable.

Selection of the Donor Site

A small amount of the body’s own adipose tissue is required for the procedure. Suitable harvest sites include the abdomen, flanks, or thighs. The selected area is disinfected and locally anesthetized prior to tissue harvesting.

Targeted Fat Harvesting

Following local anesthesia, the adipose tissue is gently harvested under sterile conditions using a fine cannula. Only a small volume required for the regenerative hair treatment is extracted.

Processing into Microfat

The harvested tissue is gently processed using the SEFFI technique through purely mechanical means, without enzymes or chemical additives. This yields a cell-rich fraction containing intact tissue clusters.

Injection into the Scalp

The processed fraction is precisely administered into the thinning areas of the scalp. Micro-injections are distributed around the weakened hair follicles to exert their regenerative effect directly at the target site.

Aftercare & Follow-up

The scalp should initially be protected; we will discuss specific recommendations regarding hair washing, sun exposure, exercise, and follow-up visits in person. Improvements in hair density and hair quality develop progressively over several months.

The Mechanism of Action of SeffiHair®

The procedure utilizes regenerative cellular components from the body’s own adipose tissue to provide biological support to the microenvironment of weakened hair follicles. The administered microfat contains components of a stromal vascular fraction (SVF) with adipose-derived stem cells (ADSCs), growth factors, and signaling molecules, which are recognized for their stimulating effects on microcirculation and the cellular environment of the scalp.
Fachärztliche Durchführung einer SeffiHair-Behandlung in Hamburg.

The Scientific Explanation

The regenerative effect is driven by the cellular diversity of the stromal vascular fraction: in addition to adipose-derived stem and stromal cells (ADSCs), it contains vascular progenitor cells and connective tissue cells that interact closely within adipose tissue. Their mechanism of action is primarily paracrine—meaning they do not differentiate into hair fibers themselves, but instead release messenger substances: growth factors and signaling molecules intended to stimulate angiogenesis (formation of new blood vessels) and support the hair root microenvironment.

For the hair follicle, the follicular niche is critical—the cellular microenvironment that co-determines whether a follicle remains in its active growth phase (anagen). Around weakened, yet still active follicles, improved microcirculation and an optimized tissue environment are intended to support this niche.

Possible Side Effects and Contraindications

Side Effects:
Contraindications:

Combination with Other Hair Therapies

Hair loss rarely has a single cause. Genetic predisposition, hormonal influences, inflammation, scalp environment, microcirculation, stress, nutritional deficiencies, or past periods of physiological stress can overlap. Therefore, SeffiHair® is not viewed in isolation, but is part of our comprehensive hair therapy concept.

PRP / PRF

Blood-based procedures utilizing growth factors; can complement SeffiHair® when repeated regenerative stimuli are indicated.

Regenera Activa®

Autologous procedure utilizing micrografts from scalp tissue; a different approach than SeffiHair®, yet closely related in purpose.

Minoxidil

Can support the hair cycle and, depending on the diagnosis, be combined with regenerative procedures.

Finasteride / Dutasteride

Address androgenetic alopecia at the hormonal level; SeffiHair® can be evaluated here as an adjunctive option.

Medical Head Spa

Supportive scalp care and stimulation; useful as a complementary component, but not a substitute for medical therapy.

Hair Transplantation

Often the more definitive approach when follicles are permanently lost; SeffiHair® can be discussed as an adjunctive measure to support the scalp.

Your Appointment for Improved Hair Health – SeffiHair® Hamburg

There is usually no single standard solution for hair loss. It is therefore crucial for us to understand the underlying causes in your individual case early on: What is causing the thinning? How active is the process? Which treatment matches your clinical findings?

SeffiHair® is a compelling option when biologically responsive hair follicles are still present and regenerative support of the scalp is indicated. Book your appointment for an initial consultation and examination, and together we will map out your path to healthier hair.

Frequently Asked Questions About SeffiHair

Is SeffiHair® the same as a hair transplant?

No. A hair transplant relocates existing hair follicles from a donor region into balding areas. Our treatment does not transplant follicles; instead, it delivers a regenerative cellular fraction from your adipose tissue into the scalp to support existing, weakened follicles. In advanced stages, both procedures can complement each other.
Yes. Hereditary hair loss affects both women and men, but in women it frequently manifests as diffuse thinning along the part line rather than a receding hairline. For early to moderate thinning, this treatment may also be considered; we assess suitability based on your clinical findings.
Hereditary hair loss is a progressive process that even the SEFFI technique cannot stop permanently. The treatment is aimed at supporting the follicular environment over an extended period; a touch-up session is advisable between 6 and 12 months, depending on your individual progress. Usually, a single session is sufficient. However, if hair loss is more pronounced, 2–3 sessions spaced 4 to 12 weeks apart may be necessary.
We make the progress measurable rather than merely observing it. We document baseline findings and development through follow-up appointments—supplemented when needed with TrichoScan analysis and standardized photo documentation, typically after 3, 6, and 12 months. This allows us to accurately assess changes in hair density and growth.
When hair follicles are permanently lost, scarred, or can no longer be activated, the potential of a regenerative treatment is limited. In cases of advanced hair loss, a hair transplant or an alternative therapeutic concept may therefore be more suitable.
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